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September 2014

Volume 1 Issue 1


Research Article

Virulent Helicobacter pylori in Dental Plaque and Gastric Specimen Samples

Amin Talebi Bezmin Abadi*, Mona Karbalayi, Ashraf Mohabati Mobarez, Mohsen Amini

The aim of study is to investigate the presence of H. pylori in dental plaque and sections of gastric mucosa in patients with dyspepsia and association with oral hygiene statues.  Helicobacter pylori (H. pylori) infection is considered as one of the most prevalent infectious agents worldwide. The prevalence of this gastric microorganism varies between 85-90% in developing countries and 20 -35% in developed countries.                                                                                                   

                                                                                                                                                             Download PDF Full text__________________________________________________________________________________________________

Mini Review

Helicobacter pylori Infection: Protective Agent against Mycobacterium tuberculosis

Amin Talebi Bezmin Abadi*

Tuberculosis (TB) is one of the world’s most deadly and contagious diseases (eight and two millions of new infected cases and deaths annually, respectively). Similarly to other infectious agents, antibiotic therapies are  applied to eliminate this  microorganism in symptomatic individuals. Strikingly, due to the frequently failed therapies, we have observed  increasing numbers of resistant microorganisms in the biologic world.                                                                                                  

                                                                                                                                                             Download PDF Full text__________________________________________________________________________________________________

 Research Article

 Increased Expression of Hepatic Endothelin1- during Fibrosis Progression in Non-alcoholic Fatty Liver Disease

 Che-Chang Chan*, Kuei-Chuan Lee, Han-Chieh Lin, Fa-Yauh Lee and Shiow-Chwen Tsai

Non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis, steatohepatitis (NASH) to fibrosis and cirrhosis. The mechanism by which NASH progresses to fibrosis has not been fully realized. Endothlein-1 (ET-1) is a strong profibrogenic factor which may play a role in the fibrosis progression of NAFLD, particularly after the development of NASH.                                                                                                   

                                                                                                                                                             Download PDF Full text__________________________________________________________________________________________________

Letter to Editor

4d Ultrasonography for Therapeutic Radiofrequency Ablation for Hepatocellular Carcinoma

Naoki Hotta*

Studies to evaluate the tumor vascularity in HCC have been done extensively with various imaging modalities because the finding of the vasularity is helpful to evaluate the biological features of the tumor. In the  present study, we  investigated whether 4D real-time  flow imaging is useful to  display the accurate position of percutaneous  radiofrequency ablation (RFA) needle in the  tumor and evaluated the efficacy of RFA therapy in patients with HCC.                                                                                                   

                                                                                                                                                             Download PDF Full text__________________________________________________________________________________________________

Research Article

Autoamputation with Band Ligation: Safe and Effective Endotherapy for Small Esophageal and Gastric Subepithelial Lesions

John Scherer, MD; Julie Holinga, MD; Jennifer Chennat, MD; Asif Khalid, MD; Michael Sanders, MD; Kenneth Fasanella, MD, Kevin McGrath, MD*

Subepithelial esophageal and gastric lesions comprise a heterogeneous group, some of which harbor malignant potential. Current clinical guidelines are outdated and incomplete regarding the optimal management of subepithelial lesions.To evaluate the efficacy and safety of endoscopic ultrasound (EUS)-guided endoscopic band ligation (EBL) for autoamputation of small esophageal and gastric subepithelial lesions.                                                                                               

                                                                                                                                                             Download PDF Full text__________________________________________________________________________________________________

Case Report

Right Lower Quadrant Abdominal Pain and Focal Ischemic Colitis

Monjur Ahmed*

Ischemic colitis is the most common form of intestinal vasculopathy. Typical presentation include moderate left lower quadrant pain, tenderness and hematochezia. Right lower quadrant pain can occur if there is associated small bowel ischemia as well due to superior mesenteric artery occlusion and in that case patients present with severe pain, hematochezia and shock.                                                                                                   

                                                                                                                                                             Download PDF Full text

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